This cancer treatment workers toolbox talk template from Health & Safety Zone provides a detailed safety briefing for employers supporting staff undergoing cancer therapy. It covers key hazards such as treatment‑related fatigue, immunosuppression, chemotherapy chemical exposure, and cognitive side‑effects. The template outlines practical control measures, including flexible working patterns, enhanced infection control, suitable PPE, indoor air quality management and mental‑health support. It is suitable for manufacturing, healthcare, construction, retail, office and public sector environments where employees may be undergoing radiotherapy or chemotherapy. Compliance with the Equality Act 2010, Health and Safety at Work Act 1974, Working Time Regulations 1998 and BS EN ISO 45001 is built into the recommendations. Use this toolbox talk to demonstrate a proactive health‑and‑safety culture, reduce sickness absence, improve morale and meet statutory duties while protecting vulnerable workers. The guide includes ready‑to‑use risk‑assessment worksheets, signage examples and a checklist for daily monitoring. By integrating this toolbox talk into induction and regular briefings, supervisors can ensure consistent messaging and auditability. Employers can customise the document to reflect specific chemotherapy agents, local ventilation requirements and shift patterns, making it a versatile resource for any organisation committed to inclusive workplace practices. Equality Act 2010 – Section 39, HSG 256 – Managing shift work (fatigue) and Working Time Regulations 1998 provide further guidance.